Title:
Evaluation of Cytotoxic and Genotoxic Effects in Human Peripheral Blood Leukocytes Following Exposure to 1950-MHz Modulated Signal
Author(s):
Anna Sannino, Maria Lucia Calabrese, Guglielmo d’Ambrosio, Rita Massa, Giovanni Petraglia, Paolo Mita, Maurizio Sarti, and Maria Rosaria Scarfì
Source:
IEEE TRANSACTIONS ON PLASMA SCIENCE
Vol./Issue/Date:
VOL. 34, NO. 4, AUGUST 2006
Year:
2006
Page(s):
1441-1448
Keywords:
Cell viability, comet assay, human leukocytes,
radio-frequency radiation, Universal Mobile Telecommunication
System (UMTS) signal.
Abstract:
Human peripheral blood leukocytes from six volunteers
were exposed to a Universal Mobile Telecommunication
System (UMTS) signal (frequency carrier of 1950 MHz) for 24 h.
The exposures were carried out in a waveguide system at specific
absorption rates (SAR) of 0.5 and 2.0 W/kg, and for each blood
donor, sham-exposed samples were also set up. The alkaline comet
assay was used to quantify DNA damage, while cytotoxicity was
determined by the Trypan blue exclusion method. The results
obtained indicate the absence of genotoxic and cytotoxic effects
at both SAR levels investigated, as assessed by comparing shamexposed
and exposed samples. Therefore, the findings indicate
that, in the experimental conditions adopted, 24-h in vitro exposure
to 1950-MHz radio-frequency radiation (UMTS signal) does not
induce DNA damage in human leukocytes.
Document:
Reference Id:
314
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