CST – Computer Simulation Technology

A multi-sample 94 GHz dissolution dynamic-nuclear-polarization system
Michael Batel, Marcin Krajewski, Kilian Weiss, Oliver With, Alexander Däpp, Andreas Hunkeler, Martin Gimersky, Klaas P. Pruessmann , Peter Boesiger, Beat H. Meier, Sebastian Kozerke, Matthias Ernst
Journal of Magnetic Resonance
Volume: 214, Issue: 1, January 2012
Dynamic nuclear polarization, Dissolution DNP, Multi-sample DNP, Hyperpolarization, Longitudinal detection EPR (LOD), Hardware
We describe the design and initial performance results of a multi-sample dissolution dynamicnuclear-polarization (DNP) polarizer based on a Helium-temperature NMR cryostat for use in a wide-bore NMR magnet with a room-temperature bore. The system is designed to accommodate up to six samples in a revolver-style sample changer that allows changing samples at liquid-Helium temperature and at pressures ranging from ambient pressure down to 1 mbar. The multi-sample setup is motivated by the desire to do repetitive in vivo measurements and to characterize the DNP process by investigating samples of different chemical composition. The system can be loaded with up to six samples simultaneously to reduce sample loading and unloading. Therefore, series of experiments can be carried out faster and more reliably. The DNP probe contains an oversized microwave cavity and includes EPR and NMR capabilities for monitoring the DNP process. In the solid state, DNP enhancements corresponding to 45% polarization for [1-13C]pyruvic acid with a trityl radical have been measured. In the initial liquid-state acquisition experiments described here, the polarization was found to be 13%, corresponding to an enhancement factor exceeding 16,000 relative to thermal polarization at 9.4 T and ambient temperature.

Back to References

contact support

Your session has expired. Redirecting you to the login page...

We use cookie to operate this website, improve its usability, personalize your experience, and track visits. By continuing to use this site, you are consenting to use of cookies. You have the possibility to manage the parameters and choose whether to accept certain cookies while on the site. For more information, please read our updated privacy policy

Cookie Management

When you browse our website, cookies are enabled by default and data may be read or stored locally on your device. You can set your preferences below:

Functional cookies

These cookies enable additional functionality like saving preferences, allowing social interactions and analyzing usage for site optimization.

Advertising cookies

These cookies enable us and third parties to serve ads that are relevant to your interests.